王松,李术钗,吴曙光,艾世鹏,钱宁,等.健体Ⅰ号对运动性疲劳大鼠抗疲劳效果的观察[J].北京体育大学学报,2012,35(3):60-62.
健体Ⅰ号对运动性疲劳大鼠抗疲劳效果的观察
Observation of the Anti fatigue Effect of ‘Jianti No.1’ on t he Exercising Fatigue Rats
投稿时间:2011-03-30  
DOI:
中文关键词:  健体Ⅰ号  运动性疲劳  肌酸激酶  糖元
英文关键词:Jianti No.1  exercise induced fatigue  CK  glycogen
基金项目:贵州省教育厅自然科学研究项目(黔教科2007036);院内 项目(504021703-042-090801)。通讯作者:钱宁
作者单位
王松 贵阳中医学院贵州 贵阳 550002 
李术钗 遵义医药高等专科学校 贵州 遵义 563002 
吴曙光 贵阳中医学院贵州 贵阳 550002 
艾世鹏 贵阳中医学院贵州 贵阳 550002 
钱宁 贵阳中医学院贵州 贵阳 550002 
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中文摘要:
      目的:观察运动性疲劳对SD大鼠血清肌酸激酶(CK)与糖元含量的影响,探讨中药复方健体I号 对运动性疲劳的预防作用。方法:30只SD大鼠随机分为正常组、模型组、实验组。模型组及 实验组大鼠进行3周每天4 h的游泳训练,实验组游泳前30 min予16.8 g/kg/d剂量健体I号水 煎液,模型组予同等量的生理盐水,正常组不作任何处理。于3周后取样测定血清肌酸激酶 、血糖、肝糖原、肌糖原及取肝肾组织作病理切片检查。观察运动性疲劳大鼠血清CK、肌糖 元、肝糖元 的变化及中药复方健体I号水煎液对上述指标的影响。结果:与正常组比较,模型 组的血清肌酸激酶含量明显偏高(P<0.05),糖元含量(P<0.01)偏低,实验组能明显降 低血清肌酸激酶含量(P<0.01),提高糖元含量(P<001),肝组织细胞水样变性明显减 轻。结论:健体I号具有抗运动性疲劳,提高运动能力的作用。
英文摘要:
      Objective: to observe the effect of exercise induced fatigue on the content of serum CK and glycogen in SD rats, and explore the prevention of exercise induce d fatigue by the “Jianti No.1”. Method: dividing 30 SD rats into normal, con trol and experimental groups at random. rats in experimental group and control g roup had 4 hour swimming every day for 3 weeks, and rats in normal group lived naturally. 30 minutes before the swimming, rats in experimental group were give n Jianti No.1 decoction 16.8 grams per kilogram everyday and the same amount o f saline to the control group. At the end of the three weeks, serum CK, blood su gar and glycogen content in rats was measured, the liver and kidney biopsy were made to compare the differences result of each group. Result: Comparation with normal group rats, CK content of rats in experimental group decreased significan tly(P<0.05) and glycogen content improved(P<0.01), while in control gr oup, CK was on the high side(P<0.01) and glycogen low(P<0.01) obviousl y. The hydropic degeneration of liver tissue of rats in the experimental group w as visibly reduced than the control group. Conclusion: Jianti No.1 can reduce the serum levels of CK, improve the content of glycogen, and inhibit hydropic de generation of liver tissue cells. It also can prevent the exercise induced fati gue and has the exact effect at improving athletic ability.
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